Your Friday Monkey Dacker Losers
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| Hmmm, sounds good. |
Obese rhesus monkeys lost on average 11 percent of their body weight after four weeks of treatment with an experimental drug that selectively destroys the blood supply of fat tissue, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in Science Translational Medicine...
"Most drugs against obesity fail in transition between rodents and primates," Pasqualini said. "All rodent models of obesity are faulty because their metabolism and central nervous system control of appetite and satiety are very different from primates, including humans. We're greatly encouraged to see substantial weight loss in a primate model of obesity that closely matches the human condition."...
Monkeys in the studies remained bright and alert throughout, interacting with caretakers and demonstrating no signs of nausea or food avoidance. This is a potentially important finding since unpleasant side-effects have limited the use of approved drugs that reduce fat absorption in the intestines.
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